A Rose with Starry Eyes

{March 18, 2010}   starting CRON info

Important & Helpful Links




Testing & Biomarkers

Tiers one and two are essentail, tier three is helpful but not neccessary.

  • Tier 1: Can be done at home.
    • Body weight (taken under same conditions each day).
    • Body temperature (and save the thermometer you use — calibrations vary slightly from thermometer to thermometer; we will at some point need to check the calibration of your thermometer).
    • Resting pulse (taken the same time each day, under the same conditions, preferably upon waking).
  • Tier 2Simple, cheap tests your doctor can easily do. (Do in morning, after having fasted for 10 – 12 hours.)
    • Basic Metabolic Panel (includes Sodium; Potassium; Calcium; Chloride; Carbon dioxide; Glucose; Blood urea nitrogen (BUN); Creatinine). See this WebMD link for details.
    • Hepatic (liver) Function Panel (includes ALT, AST, Albumin, AP, Bilirubin, and Total Protein). See this WebMD link for details.
    • Lipids Panel (includes cholesterol, high-density lipoprotein (HDL),low-density lipoprotein (LDL), and triglycerides).
    • Blood pressure (ask for this during every doctor’s appointment; also, ask for weight and temperature just for comparison with your own measurements).
    • Complete Blood Cell count (CBC) including White blood cell with differential and Red blood cell. See this WebMD link for details.
  • Tier 3: Slightly more expensive. (Listed roughly in order of importance, taken in morning, as per above.)
    • T3
    • Insulin
    • rT3
    • cortisol
    • glycated hemoglobin
    • DHEA-S
    • free testosterone
    • IGF-1
    • Albumin
  • Other useful tests:
    • Body Fat (via calipers, electronic scale/body-fat unit, buoyancy or DEXA scan method)
    • VO2 Max
    • Oral Glucose Tolerance Test (OGGT)
    • Resting Metabolic Rate (RMR)
    • DEXA scan (test for osteoporosis and general bone/skeletal health)
    • HbA1C
    • Thyroid



How Often Should The Tests Be Done?

Tier 1 tests: These are easy to do frequently. Thus, for your own records, you might find it useful to check them once a week (some people do it daily) for a few months. After that, once a month is probably fine if you don’t see much variation. For the study, we’d want whatever data you have, but would probably only need averages and/or data taken every three or six months. (Of course, if you’re gaging the degree of CR by your body weight — as opposed to by counting Calories — you probably want to weigh yourself daily.)

Tier 2 & 3 (and other more obscure blood tests): For purposes of our study, the more the better. Once or twice a year is what most people find manageable. People just starting out on CR sometimes get tested every six or even three months, since their biomarkers change so frequently in the early stages of the diet.

{March 18, 2010}   CR Article from UK

 Another CR article from the UK…

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{March 18, 2010}   PBS CRON interviews

{March 18, 2010}   UK CRON article

GREAT article on CRON diet from the UK…

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{March 18, 2010}   guest: CRON

CR is an attempt to steal more time. I’ve never seen it as much different than all the others: antibiotics, sanitation, decrease in death in childbirth, etc. Ways we cheat the jungle of nature and make our lives as humans somewhat longer, somewhat more meaningful, than a pitched battle against bacteria on one end and giant beasts on the other. The quest for serious life extension is just the same, on a grander scale. The logic of those who argue that it’s somehow immoral to want to extend your life falls apart so fast that I got bored with arguing with them.

There are, of course, ways in which we give away time. Yoga and meditation have taught me that when we sit quietly with ourselves, we win back time. We don’t have to know why it works, only that it works. When we allow ourselves to experience pure awareness, completely in the moment, we win back time.

By the same token, when we allow others to dictate our path, when we respond rather than acting upon the universe, we give up time. I’ve given away a lot. I stopped media because I realized I was giving up time. My life was being sucked up in defending myself for no good reason, so I quit. I really do have better things to do.

There are so many ways to give up our valuable time… you don’t need me to name them all. We can all think of ways we’ve wasted or given away our life energy in pursuits that really didn’t get us any closer to those we love or anything we wanted.

I put to you that life-extension is about both the physical and the spiritual. What good would it do to extend my biological lifespan if I lacked a spiritual awareness of my world as so much more than flesh and bone? And what good would it do to achieve enlightenment in a body that I was abusing with food (or anything else) to the point where I would die young? For me there’s a balance: yoga and CR, hard work and also deep meditation, a serious relationship. I expect the balance is different for everyone, but I believe it’s there.

link: http://www.mprize.org/blogs/archives/2008/12/

{March 18, 2010}   guest star: CRON

I have risked my life many times going out eating and drinking with my old best friends, in spite of MR’s sad face, so I can actually understand Bella’s decision, and that’s probably why it bothers me so much. When faced with the real prospect of immortality, how can you let anything silly like a fleeting feeling of freedom get in the way?

Of course none of us thinks we’ll be immortal. Even Aubrey de Grey doesn’t believe in that… and CR, at very most optimistic, might gain us 8 years or so. Long enough to catch the bus to radical life-extension? We hope so, but we don’t know. Some days we are more optimistic than others.

Yet there is this phenomenon among CR practitioners where the way they look seems frozen in time at the point when they started CR. They don’t age anymore. Robert K, Mary, Matt, Mike are all examples. They look the same conference after conference.

I feel like I am at a turning point. I can freeze in time where I am now, a feat that can only be accomplished by hardcore CR, or I can continue to age like the neighbors (assuming I don’t eat them) and die sooner than I had to.

The issue really is life-extension. I know CR works… I’ve known Robert K. for over five years, and he’s not aging. I live with MR, and he’s barely aging. RDF may not be consciously on CR, but is obviously doing some something with a low carb diet because he looks ten years younger than he claims to be.

The question for me re: CR is not if, it’s how. And carb restriction (moderate) seems to be working for me. MR can tell I’m thinner. My clothes are starting to fall off (not cool when you have to run to catch a flight) and I’m not hungry very often.

The great thing about low-ish carb is that it has all the fun of jumping on the back of Jacob’s motorcycle, with all the advantages of staying young and ageless with the translucent, glowing Edward. Because I was so indoctrinated into the low fat dogma as a very young woman, I get tremendous thrills out of eating FAT! Haha! Now, granted, I’m still not allowed to eat whole eggs (Edward won’t let up on that) but I do get a little bit of good girl gone bad excitement every time I eat ten more grams of almonds or pumpkin seeds. And my hair is magnificent, in a very bad-girl appropriate way. Of course, I pin it up conservatively for work.

link: http://www.mprize.org/blogs/archives/2009/12/

et cetera